Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665062 | 0.87 | MEN1 (0.62) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL8664639 | 0.80 | MEN1 (0.52) | MEN1KMT2AGAAP2RX7 | |
| SCHEMBL9013933 | 0.79 | KMT2A (0.53) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL8526757 | 0.78 | MEN1 (0.50) | MEN1KMT2AGAAALDH1A1P2RX7 | |
| SCHEMBL8479289 | 0.77 | KMT2A (0.70) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL8711149 | 0.76 | KMT2A (0.59) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL8476134 | 0.73 | KMT2A (0.75) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL8915225 | 0.73 | KMT2A (0.64) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL7162444 | 0.72 | MEN1 (0.43) | MEN1KMT2AGAAP2RX7 | |
| SCHEMBL9013865 | 0.71 | POLB (0.46) | MEN1KMT2AGAAHCRTR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821372-A | USEFUL FOR INCREASING BLOOD SERUM HIGH DENSITY LIPOPROTEIN LEVELS(HDL) | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-13 | — | — | US | disclosed |