Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.53 |
| ▸ | MEN1 | O00255 | 12/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665062 | 0.92 | MEN1 (0.62) | KMT2AMEN1GAAP2RX7HCRTR1 | |
| SCHEMBL9013774 | 0.84 | MEN1 (0.60) | KMT2AMEN1GAAP2RX7HCRTR1 | |
| SCHEMBL8479289 | 0.83 | KMT2A (0.70) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL9013865 | 0.80 | POLB (0.46) | KMT2AMEN1GAAP2RX7HCRTR1 | |
| SCHEMBL8479960 | 0.79 | KMT2A (0.48) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL8714673 | 0.79 | MEN1 (0.57) | KMT2AMEN1GAAP2RX7HCRTR1 | |
| SCHEMBL8476134 | 0.78 | KMT2A (0.75) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL8526757 | 0.78 | MEN1 (0.50) | KMT2AMEN1GAAP2RX7L3MBTL1 | |
| SCHEMBL6032861 | 0.76 | KMT2A (0.63) | KMT2AMEN1GAACYP3A4LMNA | |
| SCHEMBL8660441 | 0.75 | MEN1 (0.50) | KMT2AMEN1GAAHCRTR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |