Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013865 | 0.91 | POLB (0.46) | MEN1KMT2AGAAPOLBP2RX7 | |
| SCHEMBL8663001 | 0.89 | MEN1 (0.58) | MEN1KMT2AGAAPOLBP2RX7 | |
| SCHEMBL8665062 | 0.82 | MEN1 (0.62) | MEN1KMT2AGAAP2RX7 | |
| SCHEMBL8480499 | 0.81 | MEN1 (0.65) | MEN1KMT2AGAAPOLBP2RX7 | |
| SCHEMBL8714673 | 0.80 | MEN1 (0.57) | MEN1KMT2AGAAP2RX7 | |
| SCHEMBL8710997 | 0.79 | MEN1 (0.54) | MEN1KMT2AGAAPOLBP2RX7 | |
| SCHEMBL7162444 | 0.79 | MEN1 (0.43) | MEN1KMT2AGAAP2RX7L3MBTL1 | |
| SCHEMBL8526757 | 0.74 | MEN1 (0.50) | MEN1KMT2AGAAPOLBP2RX7 | |
| SCHEMBL8713633 | 0.73 | PKM (0.55) | MEN1KMT2AGAAPOLBL3MBTL1 | |
| SCHEMBL9819298 | 0.73 | L3MBTL1 (0.40) | MEN1KMT2APOLBP2RX7L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876355-A1 | 2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-11-11 | — | — | EP | claimed |
| WO-1997019932-A1 | 2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-05 | — | — | WO | claimed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | claimed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |