Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | RARB | P10826 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719480 | 0.91 | NR5A1 (0.66) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9074735 | 0.88 | KDM4E (0.74) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9450010 | 0.88 | KDM4E (0.74) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9618529 | 0.88 | KDM4E (0.74) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8650584 | 0.87 | NR5A1 (0.73) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL2448227 | 0.86 | KDM4E (0.72) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL13402231 | 0.84 | KDM4E (0.69) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9616908 | 0.84 | KDM4E (0.68) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9122173 | 0.84 | KDM4E (0.68) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9357415 | 0.83 | L3MBTL1 (0.64) | KDM4EALDH1A1HPGDL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849216-A | Compounds for use in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| US-5380460-A | Ferroelectric liquid crystal compounds containing chiral haloalkoxy tail units and compositions containing them | DISPLAYTECH, INC. (US) | 1995-01-10 | — | — | US | disclosed |
| WO-1993006192-A1 | FERROELECTRIC LIQUID CRYSTAL COMPOUNDS CONTAINING CHIRAL HALOALKOXY TAIL UNITS AND COMPOSITIONS CONTAINING THEM | DISPLAYTECH, INCORPORATED (US) | 1993-04-01 | — | — | WO | disclosed |