SCHEMBL8719480

SCHEMBL8719480

CCCCCCCCOc1ccc(-c2ccc(O)cc2)nc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.66
MAPT P10636 3/20 0.63
RAB9A P51151 3/20 0.63
NPC1 O15118 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
STAT3 P40763 1/20 0.63
ATM Q13315 1/20 0.63
KDM4E B2RXH2 3/20 0.63
ALDH1A1 P00352 3/20 0.63
HPGD P15428 3/20 0.63
L3MBTL1 Q9Y468 3/20 0.63
HTT P42858 1/20 0.63
LTA4H P09960 2/20 0.58
CASP3 P42574 1/20 0.51
SENP8 Q96LD8 1/20 0.51
SENP7 Q9BQF6 1/20 0.51
SENP6 Q9GZR1 1/20 0.51
CYP2D6 P10635 4/20 0.50
CYP19A1 P11511 4/20 0.50
CYP2C9 P11712 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8714797 0.91 KDM4E (0.67) NR5A1MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL9618529 0.91 KDM4E (0.74) NR5A1MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL9074735 0.91 KDM4E (0.74) NR5A1MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL9450010 0.91 KDM4E (0.74) NR5A1MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL13402231 0.88 KDM4E (0.69) NR5A1MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL9229557 0.87 CASP3 (0.68) NR5A1MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL13402174 0.87 KDM4E (0.64) NR5A1MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL8650584 0.87 NR5A1 (0.73) NR5A1MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL9814407 0.85 L3MBTL1 (0.63) NR5A1MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL10556070 0.84 RAB9A (0.68) MAPTRAB9ANPC1SMN1; SMN2STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5707545-A OPTICAL APPARATUS FOR ELCTRONICS HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-13 US disclosed
EP-0440762-B1 5-OXY-2-PHENYLPYRIDINES AND LIQUID-CRYSTAL MATERIALS HOECHST AG (DE) 1996-07-17 EP disclosed
US-5380460-A Ferroelectric liquid crystal compounds containing chiral haloalkoxy tail units and compositions containing them DISPLAYTECH, INC. (US) 1995-01-10 US disclosed
WO-1993006192-A1 FERROELECTRIC LIQUID CRYSTAL COMPOUNDS CONTAINING CHIRAL HALOALKOXY TAIL UNITS AND COMPOSITIONS CONTAINING THEM DISPLAYTECH, INCORPORATED (US) 1993-04-01 WO disclosed
US-5196141-A Electrooptical display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-03-23 US disclosed
EP-0313379-B1 OPTICALLY ACTIVE COMPOUND HAVING DELTA-VALEROLACTONE RING AND LIQUID CRYSTAL COMPOSITION COMPRISING SAME MITSUBISHI RAYON CO., LTD. (JP) 1992-07-22 EP disclosed
US-5045228-A Useful for high speed print heads MITSUBISHI RAYON COMPANY LTD. (JP) 1991-09-03 US disclosed
EP-0440762-A1 5-OXY-2-PHENYLPYRIDINES AND LIQUID-CRYSTAL MATERIALS. MERCK PATENT GMBH (DE) 1991-08-14 EP disclosed
WO-1991002722-A1 5-OXY-2-PHENYLPYRIDINES AND LIQUID-CRYSTAL MATERIALS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-03-07 WO disclosed
US-4980082-A DISPLAY ELEMENTS; HIGH SPEED RESPONSE TO ELECTRICAL FIELDS SEIKO INSTRUMENTS INC. (JP) 1990-12-25 US disclosed
EP-0313379-A2 Optically active compound having delta-valerolactone ring and liquid crystal composition comprising same MITSUBISHI RAYON CO., LTD. (JP) 1989-04-26 EP disclosed
EP-0262809-A1 Pyrimidinylphenyl ester compound TEIKOKU CHEMICAL INDUSTRY CO., LTD. (JP) 1988-04-06 EP disclosed