Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.55 |
| ▸ | PLG | P00747 | 6/20 | 0.51 |
| ▸ | PLAU | P00749 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.48 |
| ▸ | F2 | P00734 | 4/20 | 0.48 |
| ▸ | PLAT | P00750 | 4/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719907 | 0.86 | PLAU (0.48) | ITGB3ITGA2BPLGPLAUNPC1 | |
| SCHEMBL8716123 | 0.78 | ITGB3 (0.55) | ITGB3ITGA2BPLGPLAUNPC1 | |
| SCHEMBL8715677 | 0.77 | PLAU (0.48) | ITGB3ITGA2BPLGPLAUKLKB1 | |
| SCHEMBL8903362 | 0.76 | MEN1 (0.48) | ITGB3ITGA2BPLGPLAUKLKB1 | |
| SCHEMBL8717795 | 0.76 | F2 (0.57) | ITGB3ITGA2BPLGPLAUNPC1 | |
| SCHEMBL8713441 | 0.76 | MAPT (0.53) | ITGB3ITGA2BPLGPLAUKLKB1 | |
| SCHEMBL8770224 | 0.75 | ITGB3 (0.58) | ITGB3ITGA2BPLAUNPC1RAB9A | |
| SCHEMBL8770262 | 0.75 | ITGB3 (0.58) | ITGB3ITGA2BPLAUNPC1RAB9A | |
| SCHEMBL22192690 | 0.75 | KMT2A (0.72) | ITGB3ITGA2BNPC1RAB9ARXFP1 | |
| SCHEMBL8713016 | 0.75 | F2 (0.57) | ITGB3ITGA2BPLGPLAUKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |