Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770224 | 1.00 | ITGB3 (0.58) | ITGB3ITGA2BKMT2AMEN1ALDH1A1 | |
| SCHEMBL8770227 | 0.88 | NPC1 (0.51) | ITGB3ITGA2BKMT2AMEN1ALDH1A1 | |
| SCHEMBL8770638 | 0.88 | NPC1 (0.51) | ITGB3ITGA2BKMT2AMEN1ALDH1A1 | |
| SCHEMBL8770251 | 0.86 | P4HTM (0.50) | ITGB3ITGA2BKMT2AMEN1ALDH1A1 | |
| SCHEMBL8770242 | 0.85 | EPHX2 (0.51) | ITGB3ITGA2BALDH1A1NPC1RAB9A | |
| SCHEMBL8770192 | 0.84 | ITGB3 (0.51) | ITGB3ITGA2BITGB1ITGAVITGB5 | |
| SCHEMBL8770302 | 0.84 | F2 (0.49) | ITGB3ITGA2BALDH1A1NPC1RAB9A | |
| SCHEMBL8770417 | 0.84 | NPC1 (0.44) | ITGB3ITGA2BNPC1RAB9AF7 | |
| SCHEMBL7282886 | 0.83 | ITGB3 (0.65) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL7122825 | 0.82 | ITGB3 (0.75) | ITGB3ITGA2BF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | claimed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | claimed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | claimed |
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |