Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 9/20 | 0.48 |
| ▸ | PLG | P00747 | 7/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.44 |
| ▸ | F2 | P00734 | 5/20 | 0.44 |
| ▸ | PLAT | P00750 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | SCN4A | P35499 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714864 | 0.86 | ITGB3 (0.55) | PLAUPLGITGB3ITGA2BKLKB1 | |
| SCHEMBL8715803 | 0.83 | NPC1 (0.48) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL8715620 | 0.80 | PLAU (0.47) | PLAUPLGITGB3ITGA2BKLKB1 | |
| SCHEMBL8718412 | 0.80 | PLAU (0.44) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL8904735 | 0.79 | PLAU (0.44) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL8714127 | 0.79 | MAPT (0.46) | PLAUPLGITGB3ITGA2BKLKB1 | |
| SCHEMBL8718615 | 0.79 | TPSAB1 (0.52) | PLAUPLGITGB3ITGA2BKLKB1 | |
| SCHEMBL8770417 | 0.78 | NPC1 (0.44) | PLAUPLGITGB3ITGA2BPRSS1 | |
| SCHEMBL8714165 | 0.78 | F2 (0.52) | PLAUPLGITGB3ITGA2BKLKB1 | |
| SCHEMBL8904785 | 0.77 | PLAU (0.44) | PLAUPLGKLKB1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |