SCHEMBL8714931

SCHEMBL8714931

C=C=O.CC(C)(c1ccccc1)c1ccccc1O[Ti](O)(O)Oc1ccccc1C(C)(C)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 4/20 0.35
ESR1 P03372 1/20 0.35
CYP3A4 P08684 1/20 0.35
ESR2 Q92731 1/20 0.35
ALOX15 P16050 1/20 0.33
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 3/20 0.31
GAA P10253 1/20 0.31
MAPK1 P28482 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
KCNN4 O15554 1/20 0.30
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2275819 0.81 ATM (0.33) ATMTDP1ALDH1A1ESR1CYP3A4
SCHEMBL2221686 0.77 ALDH1A1 (0.39) ATMTDP1ALDH1A1ESR1CYP3A4
SCHEMBL10541515 0.72 ALDH1A1 (0.47) ATMTDP1ALDH1A1ESR1CYP3A4
SCHEMBL30545314 0.71 ALDH1A1 (0.43) ATMTDP1ALDH1A1ESR1CYP3A4
SCHEMBL9331418 0.71 ALDH1A1 (0.43) ATMTDP1ALDH1A1ESR1CYP3A4
SCHEMBL28340972 0.71 ALDH1A1 (0.43) ATMTDP1ALDH1A1ESR1CYP3A4
SCHEMBL1673996 0.71 TDP1 (0.47) ATMTDP1ALDH1A1ESR1CYP3A4
SCHEMBL1673995 0.71 TDP1 (0.47) ATMTDP1ALDH1A1ESR1CYP3A4
SCHEMBL2335330 0.70 PTGS2 (0.51) ATMTDP1ALDH1A1ESR1CYP3A4
SCHEMBL11868719 0.70 ALDH1A1 (0.41) ATMTDP1ALDH1A1ESR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5714570-A CATALYSTS CONTAINS ANTIMONY COMPOUND, TITANIUM COMPOUND AND TIN COMPOUND KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1998-02-03 US disclosed