Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.62 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | DNM2 | P50570 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3328890 | 0.77 | HTR6 (1.00) | HTR6CNR2DNM2 | |
| SCHEMBL20307301 | 0.76 | HTR6 (0.81) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL8894062 | 0.75 | HTR6 (0.67) | HTR6CNR2 | |
| SCHEMBL11831641 | 0.75 | HTR6 (0.63) | HTR6CNR2DNM2 | |
| SCHEMBL8758275 | 0.74 | HTR6 (0.67) | HTR6CNR2DNM2 | |
| SCHEMBL12558496 | 0.72 | HTR6 (0.74) | HTR6DNM2 | |
| SCHEMBL25474397 | 0.72 | DNM2 (0.68) | HTR6DNM2 | |
| SCHEMBL11829545 | 0.72 | HTR6 (0.63) | HTR6CNR2DNM2 | |
| SCHEMBL9765127 | 0.72 | HTR6 (0.61) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL31544897 | 0.70 | HTR6 (0.71) | HTR6DNM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705506-A | TREATMENT OF MIGRAINES OR HEADACHES | LABORATOIRES GLAXO SA (FR) | 1998-01-06 | — | — | US | disclosed |