Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.61 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | HTR1D | P28221 | 3/20 | 0.53 |
| ▸ | HTR1B | P28222 | 3/20 | 0.53 |
| ▸ | HTR1F | P30939 | 3/20 | 0.53 |
| ▸ | HTR7 | P34969 | 3/20 | 0.53 |
| ▸ | HTR1E | P28566 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR5A | P47898 | 1/20 | 0.53 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687324 | 0.87 | HTR1A (0.57) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| Hydrochloric Acid SCHEMBL9687692 | 0.86 | HTR1A (0.56) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL13651695 | 0.86 | HTR1A (0.56) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL9687900 | 0.85 | HTR1A (0.55) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL7476777 | 0.83 | HTR6 (0.60) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL9688466 | 0.82 | HTR1A (0.60) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL9765092 | 0.82 | PLA2G4A (0.45) | HTR6HDAC1HDAC8HDAC6PLA2G4A | |
| Oxalic Acid SCHEMBL9687340 | 0.81 | HTR2A (0.48) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL10109312 | 0.80 | HTR1A (0.56) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| Oxalic Acid SCHEMBL9597834 | 0.79 | HTR6 (0.64) | HTR6HTR1AHTR1DHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037845-A | Analgesics; for treatment or prevention of pain due to vasodilation in the cranium | GLAXO GROUP LIMITED (GB) | 1991-08-06 | — | — | US | disclosed |