Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | BAX | Q07812 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715340 | 1.00 | LMNA (0.48) | LMNAMAPK1ATML3MBTL1ESR1 | |
| SCHEMBL5690338 | 0.89 | ATM (0.58) | LMNAMAPK1ATML3MBTL1CES2 | |
| SCHEMBL11119110 | 0.89 | ATM (0.58) | LMNAMAPK1ATML3MBTL1CES2 | |
| SCHEMBL2246434 | 0.89 | ATM (0.58) | LMNAMAPK1ATML3MBTL1CES2 | |
| SCHEMBL14166103 | 0.83 | LMNA (0.46) | LMNAMAPK1ATML3MBTL1CES2 | |
| SCHEMBL1489979 | 0.82 | L3MBTL1 (0.51) | LMNAATML3MBTL1ESR1ESR2 | |
| SCHEMBL27652140 | 0.80 | MAPT (0.58) | LMNAMAPK1ATML3MBTL1ELANE | |
| SCHEMBL20943611 | 0.79 | MGLL (0.54) | CES2CES1GAAHTTALDH1A1 | |
| SCHEMBL14813083 | 0.79 | F2 (0.49) | ATMESR1ESR2ELANEHIF1A | |
| P-Cresol SCHEMBL1867060 | 0.77 | L3MBTL1 (0.54) | LMNAATML3MBTL1ELANEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873444-A1 | ENZYMATIC METHOD FOR TEXTILE DYEING | Novo Nordisk Biochem North America (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997023685-A1 | ENZYMATIC METHOD FOR TEXTILE DYEING | NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) | 1997-07-03 | — | — | WO | disclosed |