Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711081 | 0.84 | ALDH1A1 (0.33) | TTRNOX1MAOAMEN1ADRA2A | |
| SCHEMBL341222 | 0.81 | MAOA (0.43) | TTRNOX1MAOAMEN1ADRA2A | |
| SCHEMBL23051919 | 0.78 | OPRK1 (0.35) | MAOAMEN1ADRA2AADRA2BADRA2C | |
| SCHEMBL7766397 | 0.71 | — | — | |
| SCHEMBL8711778 | 0.70 | MAOA (0.61) | NOX1MAOAMEN1ADRA2AADRA2B | |
| SCHEMBL8711777 | 0.70 | CHRNA7 (0.44) | CHRM3 | |
| SCHEMBL8711901 | 0.68 | MAOA (0.53) | MAOA | |
| SCHEMBL8196598 | 0.67 | HTR2A (0.39) | MEN1ADRA2AADRA2BADRA2CCHRM3 | |
| SCHEMBL2500814 | 0.67 | CA1 (0.43) | — | |
| SCHEMBL14288809 | 0.66 | TTR (0.50) | TTRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830902-A | SQUALENE SYNTHASE INHIBITOR | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| CN-1177353-A | Novel quinuclidine derivatives having tricyclic fused hereto ring | YAMANOUCHI PHARMA CO LTD (JP) | 1998-03-25 | — | — | CN | disclosed |
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |