Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11482572 | 0.83 | MEN1 (0.47) | MEN1KMT2AHTR2AHTR2BHTR2C | |
| SCHEMBL8430263 | 0.82 | SIGMAR1 (0.50) | HTR2ASIGMAR1CYP1A2CYP2D6TSHR | |
| SCHEMBL8718156 | 0.82 | SIGMAR1 (0.42) | KMT2AHTR2ASIGMAR1ADRA2CSLC6A4 | |
| SCHEMBL8718245 | 0.81 | PNMT (0.42) | HTR2ASIGMAR1TSHRADRA2CSLC6A4 | |
| SCHEMBL8714022 | 0.78 | SIGMAR1 (0.43) | MEN1KMT2APPARGHTR2AHTR2B | |
| SCHEMBL9155234 | 0.78 | MEN1 (0.62) | MEN1KMT2AHTR2AHTR2BHTR2C | |
| SCHEMBL9472455 | 0.78 | MEN1 (0.62) | MEN1KMT2AHTR2AHTR2BHTR2C | |
| SCHEMBL27740636 | 0.77 | HTR2A (0.55) | MEN1KMT2APPARGPPARAHTR2A | |
| Hydrochloric Acid SCHEMBL9472496 | 0.77 | MEN1 (0.61) | MEN1KMT2AHTR2AHTR2BHTR2C | |
| Hydrochloric Acid SCHEMBL9472489 | 0.77 | MEN1 (0.61) | MEN1KMT2AHTR2AHTR2BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |