Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430263 | 0.87 | SIGMAR1 (0.50) | SIGMAR1SLC6A2SLC6A4SLC6A3ADRA2B | |
| SCHEMBL8718245 | 0.85 | PNMT (0.42) | SIGMAR1HTTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8714022 | 0.82 | SIGMAR1 (0.43) | SIGMAR1RAB9AALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL8715430 | 0.82 | MEN1 (0.52) | SIGMAR1ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8713645 | 0.80 | SIGMAR1 (0.44) | SIGMAR1SLC6A2SLC6A4SLC6A3ADRA2B | |
| SCHEMBL8714181 | 0.77 | SIGMAR1 (0.40) | SIGMAR1SLC6A2SLC6A4SLC6A3ADRA2B | |
| SCHEMBL8716243 | 0.77 | ACHE (0.46) | SIGMAR1ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8713177 | 0.77 | SIGMAR1 (0.40) | SIGMAR1HTTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8714206 | 0.77 | SIGMAR1 (0.44) | SIGMAR1SLC6A2SLC6A4SLC6A3ADRA2B | |
| SCHEMBL8714026 | 0.76 | MAOB (0.49) | SIGMAR1MAOAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |