Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581534 | 0.81 | CYP19A1 (0.59) | CYP19A1TDP1MAPTRAB9ANFKB1 | |
| SCHEMBL20588052 | 0.81 | CYP19A1 (0.59) | CYP19A1TDP1MAPTRAB9ANFKB1 | |
| SCHEMBL29673242 | 0.81 | CYP19A1 (0.59) | CYP19A1TDP1MAPTRAB9ANFKB1 | |
| SCHEMBL28406603 | 0.80 | CYP19A1 (0.73) | CYP19A1TDP1MAPTRAB9ANFKB1 | |
| SCHEMBL30287350 | 0.80 | CYP19A1 (0.73) | CYP19A1TDP1MAPTRAB9ANFKB1 | |
| SCHEMBL6579923 | 0.76 | CYP19A1 (0.51) | CYP19A1TDP1MAPTRAB9ANFKB1 | |
| SCHEMBL14488273 | 0.75 | CYP19A1 (0.56) | CYP19A1TDP1MAPTRAB9ANFKB1 | |
| SCHEMBL8838312 | 0.74 | CYP19A1 (0.49) | CYP19A1TDP1MAPTRAB9ANFKB1 | |
| SCHEMBL855317 | 0.74 | ADORA3 (0.59) | CYP19A1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8838311 | 0.74 | CYP19A1 (0.48) | CYP19A1TDP1MAPTRAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998023155-A1 | ARTHROPODICIDAL AND FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |
| WO-1997000612-A1 | ARTHROPODICIDAL AND FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-09 | — | — | WO | disclosed |