Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29266155 | 0.99 | THRA (0.43) | TLR8THRBTHRAMAPTLIPG | |
| SCHEMBL29266169 | 0.99 | THRA (0.43) | TLR8THRBTHRAMAPTLIPG | |
| SCHEMBL8741109 | 0.99 | THRA (0.43) | TLR8THRBTHRAMAPTLIPG | |
| SCHEMBL8718986 | 0.99 | THRA (0.43) | TLR8THRBTHRAMAPTLIPG | |
| SCHEMBL8717051 | 0.95 | TLR8 (0.40) | TLR8THRBTHRAMAPTTDP1 | |
| SCHEMBL8717783 | 0.89 | GPR84 (0.38) | THRBGAAMEN1KMT2AKDM4E | |
| SCHEMBL8712775 | 0.86 | GAA (0.46) | TLR8THRBTHRAMAPTLIPG | |
| SCHEMBL9572170 | 0.85 | THRA (0.46) | TLR8THRBTHRAMAPTLIPG | |
| SCHEMBL9572167 | 0.85 | THRA (0.46) | TLR8THRBTHRAMAPTLIPG | |
| SCHEMBL8712813 | 0.85 | THRA (0.46) | TLR8THRBTHRAMAPTLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35773-E | SILOXANE-ADDITION POLYMER COMPOSITE | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-04-21 | — | — | US | disclosed |
| US-5558803-A | ADDITION-CONDENSATION GRAFT COPOLYMERS FOR DIELECTRIC PARTICLES AND INSULATING LIQUIDS | NIPPON SHOKUBAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5376294-A | A dielectric particle and a polysiloxane/acrylic ester additive in a dielectric dispersant medium; large shear stress and low current density; stability; nonsettling | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |