Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717051 | 0.91 | TLR8 (0.40) | ATMCYP1A2GAAMEN1KMT2A | |
| SCHEMBL8715524 | 0.89 | TLR8 (0.41) | ALDH1A1HSD17B10GAAMEN1KMT2A | |
| SCHEMBL8741109 | 0.88 | THRA (0.43) | ALDH1A1HSD17B10GAAMEN1KMT2A | |
| SCHEMBL29266155 | 0.88 | THRA (0.43) | ALDH1A1HSD17B10GAAMEN1KMT2A | |
| SCHEMBL29266169 | 0.88 | THRA (0.43) | ALDH1A1HSD17B10GAAMEN1KMT2A | |
| SCHEMBL8718986 | 0.88 | THRA (0.43) | ALDH1A1HSD17B10GAAMEN1KMT2A | |
| SCHEMBL8715352 | 0.87 | CYP1A2 (0.40) | ATMALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL4525804 | 0.85 | ATM (0.43) | GPR84ATMALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL6402798 | 0.82 | ALDH1A1 (0.35) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL8713224 | 0.81 | HPRT1 (0.45) | GPR84ATMALDH1A1HSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35773-E | SILOXANE-ADDITION POLYMER COMPOSITE | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-04-21 | — | — | US | disclosed |
| US-5558803-A | ADDITION-CONDENSATION GRAFT COPOLYMERS FOR DIELECTRIC PARTICLES AND INSULATING LIQUIDS | NIPPON SHOKUBAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5376294-A | A dielectric particle and a polysiloxane/acrylic ester additive in a dielectric dispersant medium; large shear stress and low current density; stability; nonsettling | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |