Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.74 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | MMP16 | P51512 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912891 | 0.87 | HTR6 (0.53) | HTR6NFE2L2KMT2A | |
| SCHEMBL6913555 | 0.85 | HTR6 (1.00) | HTR6KDM4ETP53RXFP1MMP2 | |
| SCHEMBL7896731 | 0.85 | HTR6 (0.57) | HTR6EGFRGAANFE2L2MEN1 | |
| SCHEMBL27950989 | 0.82 | HTR6 (0.50) | HTR6GAANFE2L2ABCC9ABCC8 | |
| SCHEMBL17472499 | 0.81 | HTR6 (0.72) | HTR6KDM4ETP53RXFP1MMP2 | |
| SCHEMBL16494447 | 0.80 | HTR6 (0.70) | HTR6EGFRKDM4ETP53RXFP1 | |
| SCHEMBL3166338 | 0.79 | NFE2L2 (0.59) | HTR6NFE2L2 | |
| SCHEMBL3166330 | 0.79 | NFE2L2 (0.59) | HTR6NFE2L2 | |
| SCHEMBL14062243 | 0.79 | HTR6 (0.58) | HTR6KDM4EGAAMMP2MMP8 | |
| SCHEMBL9252637 | 0.78 | SMN1; SMN2 (0.47) | HTR6NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103588720-B | Benzo [the synthetic method of c] isoxazole-3 (1H)-one | HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-103588720-A | Synthesis method of benzo [c] isoxazole-3(1H)-ketone | UNIV HEBEI SCIENCE & TECH | 2014-02-19 | — | — | CN | disclosed |
| EP-0860429-A1 | DIPHENYL SULFONE CROSSLINKING TYPE COMPOUNDS AND RECORDING MATERIALS USING THEM | NIPPON SODA CO., LTD. (JP) | 1998-08-26 | — | — | EP | disclosed |