Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.39 |
| ▸ | FBP1 | P09467 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045061 | 0.94 | F2RL3 (0.42) | F2RL3ALDH1A1HPGDTDP1GAA | |
| SCHEMBL8045654 | 0.89 | ALDH1A1 (0.47) | FBP1ALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL8044113 | 0.79 | F2RL3 (0.44) | F2RL3ALDH1A1HPGDTDP1DRD2 | |
| SCHEMBL8711425 | 0.79 | ELANE (0.41) | F2RL3FBP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8045244 | 0.79 | F2RL3 (0.42) | F2RL3ALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL8711423 | 0.78 | GAA (0.37) | F2RL3FBP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8033176 | 0.77 | HSP90AA1 (0.44) | F2RL3ALDH1A1HPGDTDP1GAA | |
| SCHEMBL8032982 | 0.75 | RAB9A (0.40) | F2RL3ALDH1A1HPGDTDP1GAA | |
| SCHEMBL8041887 | 0.75 | HSP90AA1 (0.47) | F2RL3ALDH1A1HPGDTDP1GAA | |
| SCHEMBL8032825 | 0.74 | HSP90AA1 (0.40) | F2RL3ALDH1A1HPGDTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998027092-A1 | THIAZOLE COMPOUNDS AND METHODS OF MODULATING SIGNAL TRANSDUCTION | SUGEN, INC. (US) | 1998-06-25 | — | — | WO | disclosed |