Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 6/20 | 0.73 |
| ▸ | MMP2 | P08253 | 5/20 | 0.73 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.57 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.52 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715885 | 1.00 | MMP9 (0.73) | MMP9MMP2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7955730 | 0.86 | SLC1A3 (0.64) | MMP9MMP2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6964707 | 0.86 | SLC1A3 (0.64) | MMP9MMP2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6562692 | 0.86 | MMP9 (0.87) | MMP9MMP2ITGB3ITGA2BMMP8 | |
| SCHEMBL6562688 | 0.86 | MMP9 (0.87) | MMP9MMP2ITGB3ITGA2BMMP8 | |
| Hydrochloric Acid SCHEMBL7654060 | 0.85 | SLC1A3 (0.62) | MMP9MMP2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9257772 | 0.84 | MMP9 (0.73) | MMP9MMP2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL23039634 | 0.84 | HDAC1 (0.56) | MMP9MMP2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8993739 | 0.84 | MMP9 (0.71) | MMP9MMP2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8622042 | 0.84 | MMP9 (0.71) | MMP9MMP2SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822939-A1 | CYCLIC PENTAPEPTIDE LH-RH RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996034012-A1 | CYCLIC PENTAPEPTIDE LH-RH RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |