Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 13/20 | 0.71 |
| ▸ | MMP8 | P22894 | 5/20 | 0.71 |
| ▸ | MMP13 | P45452 | 1/20 | 0.71 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 12/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.57 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | MMP12 | P39900 | 4/20 | 0.54 |
| ▸ | MMP14 | P50281 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622042 | 1.00 | MMP9 (0.71) | MMP9MMP8MMP13ADAMTS4ALDH1A1 | |
| SCHEMBL9257772 | 0.90 | MMP9 (0.73) | MMP9MMP8MMP13ADAMTS4ALDH1A1 | |
| SCHEMBL8388668 | 0.86 | SLC1A3 (0.60) | MMP9MMP8MMP13ADAMTS4ALDH1A1 | |
| SCHEMBL8388664 | 0.86 | SLC1A3 (0.60) | MMP9MMP8MMP13ADAMTS4ALDH1A1 | |
| SCHEMBL7300504 | 0.86 | MMP7 (0.64) | MMP9MMP8MMP13ADAMTS4MMP2 | |
| SCHEMBL6434896 | 0.85 | SLC1A3 (0.61) | MMP9MMP8MMP13ADAMTS4ALDH1A1 | |
| SCHEMBL7340546 | 0.85 | SLC1A3 (0.61) | MMP9MMP8MMP13ADAMTS4ALDH1A1 | |
| SCHEMBL23039634 | 0.85 | HDAC1 (0.56) | MMP9MMP8MMP13ADAMTS4ALDH1A1 | |
| SCHEMBL698930 | 0.84 | MMP9 (0.86) | MMP9MMP8MMP13ADAMTS4MMP2 | |
| SCHEMBL716323 | 0.84 | MMP9 (0.86) | MMP9MMP8MMP13ADAMTS4MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489583-A | FOR TREATING OR PREVENTING THROMBOSIS | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-06 | — | — | US | disclosed |