Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ULK1 | O75385 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279036 | 0.79 | HTR2A (0.41) | LMNAMAPTHTR2AHTR2C | |
| SCHEMBL617825 | 0.78 | MAPT (0.34) | NOTUMLMNAMAPTHTR2AHTR2C | |
| SCHEMBL3663442 | 0.76 | MEN1 (0.33) | NOTUMMAPT | |
| SCHEMBL10829023 | 0.76 | HTR2A (0.41) | LMNAMAPTHTR2AHTR2C | |
| SCHEMBL6683483 | 0.75 | CA2 (0.34) | CA2CA4 | |
| SCHEMBL20562388 | 0.74 | MAPT (0.36) | NOTUMLMNAMAPTHTR2AHTR2C | |
| SCHEMBL11358289 | 0.72 | POLB (0.39) | CA2CA4MAPTHTR2AHTR2C | |
| SCHEMBL221777 | 0.72 | CA2 (0.35) | CA2CA4MAPTSMN1; SMN2 | |
| SCHEMBL3989267 | 0.71 | CA2 (0.34) | CA2CA4 | |
| SCHEMBL27756587 | 0.69 | NOTUM (0.31) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998017660-A1 | PHENYL SPIROETHERCYCLOALKYL TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1998-04-30 | — | — | WO | disclosed |