Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437895 | 0.77 | L3MBTL1 (0.33) | NPC1MAPTRAB9A | |
| SCHEMBL8715944 | 0.76 | NOTUM (0.39) | MAPTNOTUM | |
| SCHEMBL3409120 | 0.73 | AR (0.46) | MAPTHTTNPSR1AR | |
| SCHEMBL3663441 | 0.73 | CYP1A1 (0.32) | — | |
| SCHEMBL3411200 | 0.71 | S1PR1 (0.43) | AR | |
| SCHEMBL3669190 | 0.70 | S100A4 (0.32) | — | |
| SCHEMBL4439375 | 0.68 | F11 (0.33) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL13407668 | 0.68 | ALDH1A1 (0.43) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL3279036 | 0.68 | HTR2A (0.41) | MEN1MAPTHTTKMT2AAR | |
| SCHEMBL4429904 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238133-A2 | FUNGICIDAL AMIDES | E. I. du Pont de Nemours and Company (US) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009094407-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-30 | — | — | WO | disclosed |