Pyridine

Pyridine

SCHEMBL8716174

C=Cc1cccnc1-c1ccccn1.[Ru].c1ccncc1.c1ccncc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.42
KDM4E B2RXH2 8/20 0.41
LMNA P02545 4/20 0.41
HIF1A Q16665 3/20 0.41
CCR1 P32246 2/20 0.41
CCR5 P51681 2/20 0.41
CCR8 P51685 2/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
METAP1 P53582 1/20 0.41
BLM P54132 1/20 0.41
DOHH Q9BU89 1/20 0.41
P4HTM Q9NXG6 1/20 0.41
NPC1 O15118 5/20 0.37
HTT P42858 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
RAB9A P51151 4/20 0.36
TP53 P04637 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
ALOX15 P16050 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8721465 0.93 KDM4E (0.46) CYP2A6KDM4ELMNAHIF1ACCR1
Dipyridyl SCHEMBL10577644 0.92 KDM4E (0.50) CYP2A6KDM4ELMNAHIF1ACCR1
SCHEMBL608226 0.92 KDM4E (0.48) CYP2A6KDM4ELMNAHIF1ACCR1
Phosphine SCHEMBL27992711 0.90 KDM4E (0.46) CYP2A6KDM4ELMNAHIF1ACCR1
Quinoxaline SCHEMBL27559292 0.84 TGFBR1 (0.45) CYP2A6KDM4ELMNAHIF1ACCR1
SCHEMBL1256789 0.82 KDM4E (0.42) CYP2A6KDM4ELMNAHIF1ACCR1
SCHEMBL24179779 0.76 ALDH1A1 (0.41) CYP2A6KDM4ELMNAHIF1ACCR1
Pyridine SCHEMBL9334395 0.76 ALDH1A1 (0.46) CYP1A2NPC1SMN1; SMN2RAB9ATDP1
SCHEMBL890950 0.76 TRIM24 (0.48) CYP2A6KDM4ELMNAHIF1ACCR1
SCHEMBL398500 0.75 PTGS1 (0.39) CYP2A6KDM4ELMNAHIF1AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5840443-A SECONDARY CELL COMPRISING ELECTROLYTE AND TWO ELECTRODES, AT LEAST ONE COMPRISING REDOX POLYMER MATERIAL WHICH CHANGES OXIDATION STATE TO TRANSFER CHARGE MIDWEST RESEARCH INSTITUTE (US) 1998-11-24 US claimed