SCHEMBL398500

SCHEMBL398500

C=Cc1cccnc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 3/20 0.38
HTT P42858 2/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
ATR Q13535 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALOX15 P16050 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP2A6 P11509 2/20 0.35
HTR2B P41595 1/20 0.35
HTR5A P47898 1/20 0.35
TDO2 P48775 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
TSHR P16473 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24179779 0.85 ALDH1A1 (0.41) ALDH1A1KDM4EHTTLMNASMN1; SMN2
SCHEMBL29000608 0.83 TRPV1 (0.40) PTGS2ALDH1A1KDM4EHTTLMNA
SCHEMBL19153926 0.83 ALDH1A1 (0.41) ALDH1A1KDM4ELMNASMN1; SMN2TDO2
SCHEMBL4650076 0.80 TRIM24 (0.52) PTGS1PTGS2ALDH1A1KDM4EHTT
SCHEMBL9453571 0.80 PTPRC (0.42) ALDH1A1ATRTDP1CTSLPTPRC
SCHEMBL29000593 0.79 KDM4E (0.59) PTGS2ALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL29000590 0.79 RORB (0.49) PTGS1PTGS2TDO2PDE3BPDE3A
SCHEMBL608226 0.78 KDM4E (0.48) ALDH1A1KDM4EHTTLMNASMN1; SMN2
SCHEMBL8721465 0.77 KDM4E (0.46) ALDH1A1KDM4EHTTLMNASMN1; SMN2
SCHEMBL554431 0.77 PTGS1 (0.38) PTGS1PTGS2ALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110330532-B Novel phosphorescent iridium complex and preparation method and application thereof 南京邮电大学 2021-11-16 CN claimed
EP-2245683-B1 ORGANIC LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING THE SAME BOE TECHNOLOGY GROUP CO LTD (CN) 2019-08-28 EP claimed
EP-2229414-B1 POLYMER COMPRISING PHENYL PYRIDINE UNITS GEN ELECTRIC (US) 2012-08-15 EP claimed
EP-2229413-B1 POLYMER COMPRISING PHENYL PYRIDINE UNITS GEN ELECTRIC (US) 2012-07-11 EP claimed
US-8163402-B2 Polymer comprising phenyl pyridine units GENERAL ELECTRIC COMPANY (US) 2012-04-24 US claimed
US-7955720-B2 Polymer comprising phenyl pyridine units GENERAL ELECTRIC COMPANY (US) 2011-06-07 US claimed
US-20100276639-A1 POLYMER COMPRISING PHENYL PYRIDINE UNITS BOE TECHNOLOGY GROUP CO., LTD. (CN) 2010-11-04 US claimed
US-20100264370-A1 POLYMER COMPRISING PHENYL PYRIDINE UNITS BOE TECHNOLOGY GROUP CO., LTD. (CN) 2010-10-21 US claimed
EP-2229414-A1 POLYMER COMPRISING PHENYL PYRIDINE UNITS General Electric Company (US) 2010-09-22 EP claimed
EP-2229413-A1 POLYMER COMPRISING PHENYL PYRIDINE UNITS General Electric Company (US) 2010-09-22 EP claimed
US-20090208776-A1 ORGANIC OPTOELECTRONIC DEVICE AND METHOD FOR MANUFACTURING THE SAME GENERAL ELECTRIC COMPANY (US) 2009-08-20 US claimed
WO-2009082609-A1 POLYMER COMPRISING PHENYL PYRIDINE UNITS GENERAL ELECTRIC COMPANY (US) 2009-07-02 WO claimed
WO-2009082610-A1 POLYMER COMPRISING PHENYL PYRIDINE UNITS GENERAL ELECTRIC COMPANY (US) 2009-07-02 WO claimed
CN-110875435-B Coating type organic electroluminescent device, display device and lighting device including the same 乐金显示有限公司 2022-05-27 CN disclosed
CN-112300061-B Preparation method of nitrogen-containing heterocyclic diaryl ketone compound 大连理工大学 2022-02-18 CN disclosed
CN-112300061-A Preparation method of nitrogen-containing heterocyclic diaryl ketone compound 大连理工大学 2021-02-02 CN disclosed
US-6545159-B2 Suzuki coupling reaction of vinyl-phenylboronic acid and 2-bromopyridine in presence of alkali metallic base and tetrakis/triphenylphosphine/palladium to form styrenepyridine monomer KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2003-04-08 US disclosed
US-20020198346-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2002-12-26 US disclosed
US-20020198346-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2002-12-26 US disclosed
US-4299917-A IMPREGNATION OF AN ABSORBENT CARRIER WITH A SULPHONPHTHALEIN ESTER AND AN ACTIVATOR BOEHRINGER MANNEHEIM GMBH (DE) 1981-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100264370-A1 POLYMER COMPRISING PHENYL PYRIDINE UNITS C1R, C5, C1S PTGS1 394/4885PTGS2 928/4885ALDH1A1 1052/4885
US-20100276639-A1 POLYMER COMPRISING PHENYL PYRIDINE UNITS C5, C1R, C1S PTGS1 401/4885PTGS2 267/4885ALDH1A1 1844/4885
US-20020198346-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform VAT1, PBRM1, THEM6 PTGS1 123/4885PTGS2 405/4885ALDH1A1 184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.