Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24371959 | 0.80 | KMT2A (0.59) | KMT2AMEN1LTA4HALDH1A1SMN1; SMN2 | |
| SCHEMBL28902075 | 0.80 | IDO1 (0.50) | ALDH1A1SIGMAR1SMN1; SMN2F2PRSS1 | |
| SCHEMBL9232177 | 0.79 | MEN1 (0.54) | KMT2AMEN1LTA4HALDH1A1SIGMAR1 | |
| SCHEMBL1162783 | 0.76 | CYP1A2 (0.57) | KMT2AMEN1LTA4HALDH1A1SMN1; SMN2 | |
| SCHEMBL14839516 | 0.76 | TDP1 (0.60) | KMT2AMEN1LTA4HALDH1A1SMN1; SMN2 | |
| SCHEMBL9379292 | 0.76 | MMP12 (0.47) | MMP12ABCB1F2PRSS1 | |
| SCHEMBL28347286 | 0.74 | ALDH1A1 (0.60) | LTA4HALDH1A1SIGMAR1SMN1; SMN2HTT | |
| SCHEMBL28347287 | 0.74 | ALDH1A1 (0.60) | LTA4HALDH1A1SIGMAR1SMN1; SMN2HTT | |
| SCHEMBL25620278 | 0.74 | KMT2A (0.56) | KMT2AMEN1LTA4HALDH1A1SMN1; SMN2 | |
| SCHEMBL7707362 | 0.73 | IDO1 (0.47) | MMP12ABCB1F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849217-A | Optically active compound, liquid crystal composition containing the same, liquid crystal device using the same, liquid crystal apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1998-12-15 | — | — | US | disclosed |