Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201286 | 0.81 | MAPT (0.49) | TSHRMAPTTDP1KMT2AMEN1 | |
| SCHEMBL8719747 | 0.81 | TDP1 (0.49) | TSHRMAPTTDP1KMT2AMEN1 | |
| SCHEMBL8201827 | 0.80 | ALDH1A1 (0.46) | TSHRMAPTTDP1KMT2AMEN1 | |
| SCHEMBL8201916 | 0.80 | KMT2A (0.52) | TSHRMAPTTDP1KMT2AMEN1 | |
| SCHEMBL8716300 | 0.79 | MAPT (0.45) | TSHRMAPTTDP1KMT2AMEN1 | |
| SCHEMBL8204140 | 0.78 | ALDH1A1 (0.44) | TSHRMAPTTDP1KMT2AMEN1 | |
| SCHEMBL693383 | 0.75 | TDP1 (0.49) | TSHRMAPTTDP1KMT2AMEN1 | |
| SCHEMBL8202046 | 0.75 | MAPT (0.42) | TSHRMAPTTDP1KMT2AMEN1 | |
| SCHEMBL8202181 | 0.75 | TSHR (0.48) | TSHRMAPTTDP1KMT2AMEN1 | |
| SCHEMBL8201828 | 0.74 | MAPT (0.43) | TSHRMAPTTDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753700-A | ANALGESICS; CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |