Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTGIR | P43119 | 9/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202557 | 0.92 | SLC6A9 (0.48) | TDP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8202190 | 0.91 | MAPK1 (0.43) | TDP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8206250 | 0.91 | MAPT (0.47) | TDP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8202181 | 0.90 | TSHR (0.48) | TDP1KDM4EMAPTTSHRMEN1 | |
| SCHEMBL8418748 | 0.89 | KMT2A (0.53) | TDP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8417285 | 0.89 | KMT2A (0.53) | TDP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8420212 | 0.88 | ALDH1A1 (0.51) | TDP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8201828 | 0.87 | MAPT (0.43) | TDP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8206771 | 0.87 | MAPT (0.42) | TDP1MAPTTSHRSLC6A9SLC6A5 | |
| SCHEMBL8420341 | 0.86 | ALDH1A1 (0.57) | TDP1KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270489-A1 | Remedy for Cartilage-Related Diseases | ONO PHARMACEUTICAL CO., LTD. | 2007-11-22 | — | — | US | claimed |
| EP-1661580-A1 | REMEDY FOR CARTILAGE-RELATED DISEASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-05-31 | — | — | EP | claimed |
| EP-0719760-B1 | Naphthalene derivatives and their use as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1999-09-22 | — | — | EP | claimed |
| EP-0719760-A1 | Naphthyloxyacetic acid derivatives and their use as PGW2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | claimed |
| JP-8239356-A | — | — | None | — | — | JP | disclosed |
| US-20120316241-A1 | REMEDY FOR CARTILAGE-RELATED DISEASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2012-12-13 | — | — | US | disclosed |
| EP-2422814-A1 | Remedy for cartilage-related diseases | Ono Pharmaceutical Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-20070270489-A1 | Remedy for Cartilage-Related Diseases | ONO PHARMACEUTICAL CO., LTD. | 2007-11-22 | — | — | US | disclosed |
| US-20060128810-A1 | Remedies for allergic diseases | KYOTO UNIVERSITY (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1661580-A1 | REMEDY FOR CARTILAGE-RELATED DISEASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-05-31 | — | — | EP | disclosed |
| EP-1563845-A1 | REMEDIES FOR ALLERGIC DISEASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-08-17 | — | — | EP | disclosed |
| US-6013673-A | ADMINISTERING AN EFFECTIVE AMOUNT OF A NAPHTHYLOXYACETIC ACID DERIVATIVE OR NONTOXIC ACID ADDITION SALT OR HYDRATE TO TREAT OR PREVENT ABORTION, PAINE, DIARRHEA, CATHARTICS, ULCER, GASTRITIS, HYPERTENSION AND THROMBOSIS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-01-11 | — | — | US | disclosed |
| EP-0719760-B1 | Naphthalene derivatives and their use as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1999-09-22 | — | — | EP | disclosed |
| JP-H08239356-A | NAPHTHYLOXYACETIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME AS ACTIVE INGREDIENT | ONO PHARMACEUT CO LTD | 1996-09-17 | — | — | JP | disclosed |
| EP-0719760-A1 | Naphthyloxyacetic acid derivatives and their use as PGW2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270489-A1 | Remedy for Cartilage-Related Diseases | COL2A1, PTGES3, PTGER3 | TDP1 4790/4885KDM4E 4036/4885ALDH1A1 1684/4885 |
| US-20120316241-A1 | REMEDY FOR CARTILAGE-RELATED DISEASES | COL2A1, PTGES3, PTGER3 | TDP1 4790/4885KDM4E 4036/4885ALDH1A1 1684/4885 |
| US-20060128810-A1 | Remedies for allergic diseases | PTGER3, PTGER1, PTGES3 | TDP1 4838/4885KDM4E 3806/4885ALDH1A1 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.