Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.30 |
| ▸ | LATS1 | O95835 | 1/20 | 0.30 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716338 | 1.00 | MMP3 (0.33) | MMP3CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL7068624 | 0.73 | LATS1 (0.39) | MMP3HCAR3UTS2RLATS1LATS2 | |
| SCHEMBL8583950 | 0.71 | ABL1 (0.38) | MMP3GPR84 | |
| SCHEMBL7006066 | 0.70 | GPR84 (0.35) | MMP3SMN1; SMN2GPR84 | |
| SCHEMBL7070572 | 0.70 | GPR84 (0.35) | MMP3SMN1; SMN2GPR84 | |
| SCHEMBL7069174 | 0.70 | GPR84 (0.35) | MMP3SMN1; SMN2GPR84 | |
| SCHEMBL16974843 | 0.69 | ACHE (0.38) | MMP3SMN1; SMN2GPR84UTS2RCRHR1 | |
| SCHEMBL8582984 | 0.68 | MMP3 (0.33) | MMP3HCAR3GPR84 | |
| SCHEMBL7069351 | 0.66 | GPR84 (0.34) | MMP3HCAR3GPR84UTS2R | |
| SCHEMBL7069469 | 0.66 | GPR84 (0.34) | MMP3HCAR3GPR84UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876379-A1 | FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997026265-A1 | FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-24 | — | — | WO | disclosed |