Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716500 | 0.85 | ELANE (0.32) | ELANE | |
| SCHEMBL8481105 | 0.71 | — | — | |
| SCHEMBL8716353 | 0.69 | — | — | |
| SCHEMBL8715824 | 0.67 | — | — | |
| SCHEMBL8719106 | 0.64 | — | — | |
| SCHEMBL12957338 | 0.52 | PLK1 (0.59) | — | |
| SCHEMBL14094824 | 0.50 | — | — | |
| SCHEMBL21799861 | 0.49 | PLK1 (0.40) | — | |
| SCHEMBL2958217 | 0.48 | ALDH1A1 (0.40) | ELANE | |
| SCHEMBL8176841 | 0.47 | CA1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876379-A1 | FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997026265-A1 | FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-24 | — | — | WO | disclosed |