Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905478 | 1.00 | NPC1 (0.46) | NPC1RAB9ATDP1KDM4EALDH1A1 | |
| SCHEMBL8713211 | 0.90 | CETP (0.40) | NPC1RAB9ATDP1KDM4EALDH1A1 | |
| SCHEMBL8904764 | 0.90 | CETP (0.40) | NPC1RAB9ATDP1KDM4EALDH1A1 | |
| SCHEMBL8903418 | 0.87 | DRD2 (0.38) | NPC1RAB9AMCHR1CETP | |
| SCHEMBL8715011 | 0.84 | NPC1 (0.46) | NPC1RAB9ATDP1KDM4EALDH1A1 | |
| SCHEMBL8906270 | 0.84 | NPC1 (0.46) | NPC1RAB9ATDP1KDM4EALDH1A1 | |
| SCHEMBL8904770 | 0.84 | CETP (0.37) | NPC1RAB9ATDP1KDM4EALDH1A1 | |
| SCHEMBL8904014 | 0.82 | DRD2 (0.39) | NPC1RAB9AMCHR1CETP | |
| SCHEMBL8715642 | 0.82 | CETP (0.43) | NPC1RAB9AMCHR1CETP | |
| SCHEMBL8904008 | 0.82 | CETP (0.43) | NPC1RAB9AMCHR1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |