Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 9/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | UGCG | Q16739 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904008 | 1.00 | CETP (0.43) | CETPRAB9ANPC1DRD2DRD4 | |
| SCHEMBL8712830 | 0.86 | DRD2 (0.45) | RAB9ANPC1DRD2DRD4DRD3 | |
| SCHEMBL8712899 | 0.86 | CETP (0.43) | CETPDRD2DRD4DRD3HRH3 | |
| SCHEMBL8713959 | 0.84 | IRAK4 (0.40) | CETPRAB9ANPC1 | |
| SCHEMBL8906191 | 0.84 | IRAK4 (0.40) | CETPRAB9ANPC1 | |
| SCHEMBL8712867 | 0.84 | F2 (0.51) | RAB9ANPC1 | |
| SCHEMBL8904014 | 0.84 | DRD2 (0.39) | CETPRAB9ANPC1DRD2DRD3 | |
| SCHEMBL8903361 | 0.84 | F2 (0.51) | RAB9ANPC1 | |
| SCHEMBL8716441 | 0.82 | NPC1 (0.46) | CETPRAB9ANPC1MCHR1 | |
| SCHEMBL8905478 | 0.82 | NPC1 (0.46) | CETPRAB9ANPC1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |