Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 8/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904770 | 0.90 | CETP (0.37) | DRD2CETPABCB1IRAK4EGLN1 | |
| SCHEMBL8905478 | 0.87 | NPC1 (0.46) | CETPNPC1RAB9AMCHR1 | |
| SCHEMBL8716441 | 0.87 | NPC1 (0.46) | CETPNPC1RAB9AMCHR1 | |
| SCHEMBL8904014 | 0.85 | DRD2 (0.39) | DRD2CETPABCB1IRAK4PDE4B | |
| SCHEMBL8904764 | 0.84 | CETP (0.40) | DRD2CETPABCB1IRAK4NPC1 | |
| SCHEMBL8713211 | 0.84 | CETP (0.40) | DRD2CETPABCB1IRAK4NPC1 | |
| SCHEMBL8906283 | 0.83 | ITGB3 (0.40) | — | |
| SCHEMBL8715642 | 0.80 | CETP (0.43) | DRD2CETPABCB1NPC1RAB9A | |
| SCHEMBL8904008 | 0.80 | CETP (0.43) | DRD2CETPABCB1NPC1RAB9A | |
| SCHEMBL8713035 | 0.77 | DRD2 (0.49) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |