Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.55 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9231642 | 0.95 | HSD11B1 (0.50) | HSD11B1HTR2AHTR2CDRD2PTGIR | |
| Fumaric Acid SCHEMBL9231639 | 0.95 | HSD11B1 (0.50) | HSD11B1HTR2AHTR2CDRD2PTGIR | |
| SCHEMBL8710827 | 0.93 | HSD11B1 (0.54) | HSD11B1HTR2AHTR2CDRD2PTGIR | |
| Hydrochloric Acid SCHEMBL9229278 | 0.92 | HSD11B1 (0.53) | HSD11B1HTR2AHTR2CDRD2PTGIR | |
| SCHEMBL8714991 | 0.90 | HSD11B1 (0.51) | HSD11B1HTR2AHTR2CDRD2HTR7 | |
| SCHEMBL8713835 | 0.90 | HSD11B1 (0.51) | HSD11B1HTR2AHTR2CDRD2PTGIR | |
| Fumaric Acid SCHEMBL9232997 | 0.89 | HSD11B1 (0.49) | HSD11B1HTR2AHTR2CDRD2PTGIR | |
| Fumaric Acid SCHEMBL9233003 | 0.89 | HSD11B1 (0.49) | HSD11B1HTR2AHTR2CDRD2PTGIR | |
| SCHEMBL8713474 | 0.89 | ACHE (0.52) | HTR2AHTR2CPTGIRHTR7HTR6 | |
| SCHEMBL8711675 | 0.89 | HTR2A (0.51) | HTR2AHTR2CHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0661266-A1 | Substituted cyclic amine compounds as 5HT2 antagonists | TOA EIYO LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |