Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716591 | 1.00 | PPARG (0.44) | PPARGPPARASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8718438 | 0.88 | ADRA2C (0.49) | SLC6A2SLC6A3SLC6A4CYP2D6CYP2C19 | |
| SCHEMBL8718436 | 0.88 | ADRA2C (0.49) | SLC6A2SLC6A3SLC6A4CYP2D6CYP2C19 | |
| SCHEMBL8716583 | 0.87 | SLC6A2 (0.43) | PPARGPPARASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8716580 | 0.87 | SLC6A2 (0.43) | PPARGPPARASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8716623 | 0.85 | ADRB3 (0.40) | PPARGPPARAADRB2CYP1A2CYP2D6 | |
| SCHEMBL8717498 | 0.85 | CBX7 (0.45) | SLC6A2SLC6A3SLC6A4CYP2D6CYP3A4 | |
| SCHEMBL8716621 | 0.85 | ADRB3 (0.40) | PPARGPPARAADRB2CYP1A2CYP2D6 | |
| SCHEMBL8717494 | 0.85 | CBX7 (0.45) | SLC6A2SLC6A3SLC6A4CYP2D6CYP3A4 | |
| SCHEMBL8717462 | 0.83 | KMT2A (0.41) | SLC6A2SLC6A3SLC6A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |