Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718438 | 1.00 | ADRA2C (0.49) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL8716593 | 0.88 | PPARG (0.44) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL8716591 | 0.88 | PPARG (0.44) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL8714091 | 0.86 | TAAR1 (0.38) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL8714092 | 0.86 | TAAR1 (0.38) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL8716621 | 0.85 | ADRB3 (0.40) | AOC3ADRA1ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8716623 | 0.85 | ADRB3 (0.40) | AOC3ADRA1ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8713637 | 0.85 | HSD11B1 (0.36) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL8713634 | 0.85 | HSD11B1 (0.36) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL8713656 | 0.83 | LMNA (0.47) | ADRA2CKDM4EADRA2ALMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |