Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 8/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716621 | 1.00 | ADRB3 (0.40) | ADRB3PNMTTRPM8ADRB1ADRB2 | |
| SCHEMBL8719067 | 0.88 | HDAC8 (0.43) | ADRB3PNMTADRB1ADRB2HDAC8 | |
| SCHEMBL8719065 | 0.88 | HDAC8 (0.43) | ADRB3PNMTADRB1ADRB2HDAC8 | |
| SCHEMBL8716591 | 0.85 | PPARG (0.44) | ADRB2HDAC8AOC3PPARGPPARA | |
| SCHEMBL8716593 | 0.85 | PPARG (0.44) | ADRB2HDAC8AOC3PPARGPPARA | |
| SCHEMBL8718436 | 0.85 | ADRA2C (0.49) | AOC3HTR2AADRA1AMEN1CYP3A4 | |
| SCHEMBL8718438 | 0.85 | ADRA2C (0.49) | AOC3HTR2AADRA1AMEN1CYP3A4 | |
| SCHEMBL8717494 | 0.85 | CBX7 (0.45) | PNMTCYP3A4CYP2D6 | |
| SCHEMBL8717498 | 0.85 | CBX7 (0.45) | PNMTCYP3A4CYP2D6 | |
| SCHEMBL8720148 | 0.84 | ADRB3 (0.44) | ADRB3PNMTADRB1ADRB2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |