Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716601 | 1.00 | SLC6A4 (0.53) | SLC6A4CYP2D6CYP1A2CYP2C19MEN1 | |
| SCHEMBL8716253 | 0.93 | CYP1A2 (0.58) | SLC6A4CYP2D6CYP1A2CYP2C19LDHA | |
| SCHEMBL8716256 | 0.93 | CYP1A2 (0.58) | SLC6A4CYP2D6CYP1A2CYP2C19LDHA | |
| SCHEMBL8714017 | 0.86 | CYP2D6 (0.58) | SLC6A4CYP2D6ALDH1A1EPHX1ADRA2A | |
| SCHEMBL8714019 | 0.86 | CYP2D6 (0.58) | SLC6A4CYP2D6ALDH1A1EPHX1ADRA2A | |
| SCHEMBL8718471 | 0.85 | LTA4H (0.54) | MEN1KMT2ALTA4HPPARGPPARA | |
| SCHEMBL8718467 | 0.85 | LTA4H (0.54) | MEN1KMT2ALTA4HPPARGPPARA | |
| SCHEMBL8720159 | 0.85 | TAAR1 (0.60) | SLC6A4MEN1KMT2AALDH1A1ADRA2A | |
| SCHEMBL8720156 | 0.85 | TAAR1 (0.60) | SLC6A4MEN1KMT2AALDH1A1ADRA2A | |
| SCHEMBL8716718 | 0.84 | SLC6A4 (0.49) | SLC6A4CYP2D6CYP1A2CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |