Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.60 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720159 | 1.00 | TAAR1 (0.60) | TAAR1CASRSLC6A2SLC6A4ADRB2 | |
| SCHEMBL8713330 | 0.88 | TAAR1 (0.55) | TAAR1SLC6A2SLC6A4ADRB2LMNA | |
| SCHEMBL8713332 | 0.88 | TAAR1 (0.55) | TAAR1SLC6A2SLC6A4ADRB2LMNA | |
| SCHEMBL8716601 | 0.85 | SLC6A4 (0.53) | SLC6A4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL8716604 | 0.85 | SLC6A4 (0.53) | SLC6A4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL8714019 | 0.83 | CYP2D6 (0.58) | TAAR1SLC6A2SLC6A4ADRA2AADRA2C | |
| SCHEMBL8714017 | 0.83 | CYP2D6 (0.58) | TAAR1SLC6A2SLC6A4ADRA2AADRA2C | |
| SCHEMBL8713927 | 0.82 | ADRA2A (0.49) | TAAR1SLC6A2SLC6A4ADRA2AADRA2C | |
| SCHEMBL8713926 | 0.82 | ADRA2A (0.49) | TAAR1SLC6A2SLC6A4ADRA2AADRA2C | |
| SCHEMBL8713588 | 0.82 | MEN1 (0.47) | TAAR1ADRA2AADRA2CLMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |