Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.42 |
| ▸ | TK1 | P04183 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898025 | 0.78 | TYMP (0.58) | TYMPTK1MAPK1HPGD | |
| SCHEMBL8716673 | 0.73 | TYMP (0.42) | TYMPTK1MAPK1HPGD | |
| SCHEMBL8898029 | 0.72 | TYMP (0.43) | TYMPTK1MAPK1HPGD | |
| SCHEMBL6998418 | 0.70 | MAPK1 (0.43) | TYMPTK1MAPK1HPGD | |
| SCHEMBL8711443 | 0.70 | TYMP (0.51) | TYMPTK1MAPK1HPGD | |
| SCHEMBL8896625 | 0.70 | FGFR1 (0.39) | — | |
| SCHEMBL16038197 | 0.68 | TYMP (0.60) | TYMPTK1MAPK1HPGD | |
| SCHEMBL4118906 | 0.68 | TYMP (0.44) | TYMPTK1 | |
| SCHEMBL6153438 | 0.68 | MAPK1 (0.42) | TYMPTK1MAPK1HPGD | |
| SCHEMBL19662195 | 0.67 | ALDH1A1 (0.42) | TYMPTK1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837871-A | PHOSPHONATE DERIVATIVES; ANTITUMOR AGENTS, VIRICIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-11-17 | — | — | US | disclosed |
| EP-0398231-B1 | Nucleoside analogs | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1997-07-16 | — | — | EP | disclosed |
| EP-0398231-A2 | Nucleoside analogs | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1990-11-22 | — | — | EP | disclosed |