Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.34 |
| ▸ | GHSR | Q92847 | 6/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716730 | 1.00 | LTA4H (0.34) | LTA4HGHSRITGB3ITGA2BHTR5A | |
| SCHEMBL6318942 | 0.93 | LTA4H (0.38) | LTA4HGHSRITGB3ITGA2BCTSC | |
| SCHEMBL6323200 | 0.88 | MMP3 (0.38) | LTA4HGHSRMMP3 | |
| SCHEMBL6323718 | 0.88 | GHSR (0.41) | GHSRMMP3 | |
| SCHEMBL8206172 | 0.87 | GHSR (0.38) | LTA4HGHSRCTSC | |
| SCHEMBL6319415 | 0.87 | GHSR (0.38) | LTA4HGHSRCTSC | |
| SCHEMBL6323311 | 0.86 | CHRM3 (0.34) | LTA4HGHSRCTSCMMP3 | |
| SCHEMBL7162631 | 0.85 | GHSR (0.37) | LTA4HGHSRITGB3ITGA2B | |
| SCHEMBL6317890 | 0.84 | TACR1 (0.40) | LTA4HGHSR | |
| SCHEMBL6325620 | 0.83 | GHSR (0.37) | LTA4HGHSRITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869974-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-10-14 | — | — | EP | disclosed |