Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 14/20 | 0.43 |
| ▸ | ATP4B | P51164 | 14/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653167 | 0.80 | PPARD (0.45) | ATP4AATP4BKMT2AMAPT | |
| SCHEMBL4443997 | 0.78 | PPARG (0.55) | KMT2AMAPTMEN1 | |
| SCHEMBL6806950 | 0.76 | ATP4A (0.50) | ATP4AATP4BKMT2AMAPTMEN1 | |
| SCHEMBL1848107 | 0.76 | PPARG (0.47) | ATP4AATP4BKMT2AMAPTMEN1 | |
| SCHEMBL1846169 | 0.75 | PPARG (0.68) | — | |
| SCHEMBL12520389 | 0.75 | PPARG (0.68) | — | |
| SCHEMBL1848104 | 0.74 | PPARG (0.69) | — | |
| SCHEMBL1846171 | 0.73 | PPARG (0.55) | ATP4AATP4BMAPT | |
| SCHEMBL1746627 | 0.72 | PPARD (0.53) | ATP4AATP4BKMT2AMAPTMEN1 | |
| SCHEMBL18674619 | 0.71 | RAB9A (0.60) | ATP4AATP4BKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756525-A | USING A THIAZOLIDINEDIONE COMPOUND | BEECHAM GROUP PLC (GB) | 1998-05-26 | — | — | US | claimed |
| US-5756525-A | USING A THIAZOLIDINEDIONE COMPOUND | BEECHAM GROUP PLC (GB) | 1998-05-26 | — | — | US | disclosed |