Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 4/20 | 0.40 |
| ▸ | ATP4B | P51164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653163 | 0.80 | GSK3A (0.52) | PPARDPPARAALOX5MAPTL3MBTL1 | |
| SCHEMBL8649700 | 0.76 | FFAR1 (0.57) | PPARAMAPTALDH1A1FFAR1GRM2 | |
| SCHEMBL8650157 | 0.75 | FFAR1 (0.58) | PPARAMAPTFFAR1 | |
| SCHEMBL3115953 | 0.72 | ALDH1A1 (0.51) | MAPTL3MBTL1KMT2AALDH1A1POLB | |
| SCHEMBL7455599 | 0.72 | PPARD (0.44) | PPARDPPARAALOX5MAPTL3MBTL1 | |
| SCHEMBL7455591 | 0.70 | FFAR1 (0.63) | PPARAFFAR1 | |
| SCHEMBL7478013 | 0.68 | PPARD (0.58) | PPARDPPARAMAPTL3MBTL1TDP1 | |
| SCHEMBL7867091 | 0.67 | PTPN1 (0.50) | — | |
| SCHEMBL8556878 | 0.65 | PPARD (0.50) | PPARDPPARAALOX5MAPTL3MBTL1 | |
| SCHEMBL8556876 | 0.65 | ALOX5 (0.56) | PPARDPPARAALOX5MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843970-A | Thiazolidine derivatives for the treatment of hypertension | BETHESDA PHARMACEUTICALS, INC. | 1998-12-01 | — | — | US | disclosed |
| US-5824694-A | Thiazolidine derivatives for the treatment of psoriasis | BETHESDA PHARMACEUTICALS, INC. (US) | 1998-10-20 | — | — | US | disclosed |