Propionic Acid

Propionic Acid

SCHEMBL8716868

CC(C)(C)OC(=O)N1CCc2c([nH]c3ccccc23)C1.CCC(=O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 11/20 0.64
FAAH O00519 3/20 0.64
GPX4 P36969 1/20 0.57
CDK4 P11802 3/20 0.53
CCND1 P24385 3/20 0.53
HDAC1 Q13547 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50
PRMT5 O14744 1/20 0.49
WDR77 Q9BQA1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL350201 0.93 TRPV1 (0.69) TRPV1FAAHGPX4CDK4CCND1
Acetic Acid SCHEMBL8718251 0.92 TRPV1 (0.68) TRPV1FAAHGPX4CDK4CCND1
SCHEMBL6474214 0.85 LMNA (0.60) TRPV1FAAHGPX4CDK4CCND1
SCHEMBL2241936 0.84 MAPT (0.69) TRPV1FAAH
SCHEMBL29357331 0.84 MAPT (0.69) TRPV1FAAH
Acetic Acid SCHEMBL8714196 0.84 MAPT (0.68) TRPV1FAAH
SCHEMBL21154454 0.83 LMNA (0.55) TRPV1FAAHGPX4CDK4CCND1
SCHEMBL17792377 0.81 TRPV1 (0.52) TRPV1FAAHGPX4HDAC1HDAC6
SCHEMBL2270578 0.81 PARP1 (0.57) TRPV1FAAHGPX4CDK4CCND1
SCHEMBL20882095 0.81 GPX4 (0.77) TRPV1FAAHGPX4CDK4CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5817756-A USING A MODIFIED DI- OR TRI-PEPTIDES SCIOS INC. (US) 1998-10-06 US disclosed