Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640882 | 0.79 | TSHR (0.39) | GAAMGAMSIMGAM2CYP1A2 | |
| Hydrochloric Acid SCHEMBL10803853 | 0.78 | TSHR (0.39) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL22980572 | 0.77 | CYP1A2 (0.44) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL4151262 | 0.76 | GAA (0.34) | GAAMGAMSIMGAM2CTSK | |
| SCHEMBL25866514 | 0.76 | CYP1A2 (0.43) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL1696853 | 0.73 | CA12 (0.41) | EPHX2TSHR | |
| SCHEMBL14309152 | 0.73 | MGAM (0.38) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL20569336 | 0.72 | FPR3 (0.37) | — | |
| SCHEMBL8643850 | 0.72 | TSHR (0.44) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL23007925 | 0.72 | CYP1A2 (0.42) | GAAMGAMSIMGAM2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763604-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5578594-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-26 | — | — | US | disclosed |