Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | AHCY | P23526 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29239791 | 0.80 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL4151262 | 0.75 | GAA (0.34) | FPR2NFKB1NFKB2RELA | |
| SCHEMBL23849109 | 0.75 | FPR3 (0.39) | FPR3FPR2NFKB1NFKB2RELA | |
| SCHEMBL29239790 | 0.75 | DNM1 (0.36) | — | |
| SCHEMBL4144318 | 0.73 | NFKB1 (0.37) | NFKB1NFKB2RELACPB2 | |
| SCHEMBL22303932 | 0.73 | NFKB1 (0.43) | NFKB1NFKB2RELACA14 | |
| SCHEMBL30999446 | 0.73 | FPR3 (0.39) | FPR3FPR2CA14AAK1 | |
| SCHEMBL30999452 | 0.73 | FPR3 (0.39) | FPR3FPR2CA14AAK1 | |
| SCHEMBL8716878 | 0.72 | GAA (0.36) | — | |
| SCHEMBL5347434 | 0.72 | ALDH1A1 (0.38) | FPR3FPR2NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |