Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 3/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716908 | 0.85 | F2 (0.54) | MEN1KMT2APOLBALDH1A1F2 | |
| SCHEMBL8388668 | 0.81 | SLC1A3 (0.60) | POLBALDH1A1F2SLC1A3SLC1A2 | |
| SCHEMBL8388664 | 0.81 | SLC1A3 (0.60) | POLBALDH1A1F2SLC1A3SLC1A2 | |
| SCHEMBL7300504 | 0.80 | MMP7 (0.64) | POLBF2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7290941 | 0.80 | MMP2 (0.71) | POLBALDH1A1F2SLC1A3SLC1A2 | |
| SCHEMBL3310154 | 0.80 | MMP2 (0.71) | POLBALDH1A1F2SLC1A3SLC1A2 | |
| SCHEMBL5189194 | 0.80 | MMP2 (0.71) | POLBALDH1A1F2SLC1A3SLC1A2 | |
| SCHEMBL31086814 | 0.80 | MMP2 (0.71) | POLBALDH1A1F2SLC1A3SLC1A2 | |
| SCHEMBL7294588 | 0.79 | F2 (0.48) | MEN1KMT2APOLBALDH1A1F2 | |
| SCHEMBL26606049 | 0.79 | SLC1A3 (0.61) | POLBALDH1A1F2SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763604-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5677448-A | CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-10-14 | — | — | US | disclosed |
| US-5578594-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5405854-A | Anticoagulants | HOFFMANN-LA ROCHE INC. (US) | 1995-04-11 | — | — | US | disclosed |