Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717348 | 0.78 | MPO (0.38) | KDM4EHSD17B10MEN1KMT2AS1PR1 | |
| SCHEMBL8711498 | 0.64 | MEN1 (0.41) | KDM4EHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL8711714 | 0.63 | MPO (0.51) | KDM4EMEN1KMT2AHPGDMTNR1A | |
| SCHEMBL8711715 | 0.61 | MTNR1A (0.53) | KDM4EHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL8712366 | 0.61 | MPO (0.46) | MEN1KMT2AHPGDTSHRMTNR1A | |
| SCHEMBL8712074 | 0.60 | MPO (0.47) | KDM4EMEN1KMT2AHPGDMTNR1A | |
| SCHEMBL8717169 | 0.59 | MTNR1A (0.65) | KDM4EHSD17B10MEN1KMT2AHPGD | |
| SCHEMBL3916058 | 0.58 | FAAH (0.95) | MEN1KMT2AFAAH | |
| Diethylamine SCHEMBL8398221 | 0.57 | FAAH (0.83) | MEN1KMT2AFAAH | |
| N-Ethylpalmitamide SCHEMBL4148137 | 0.56 | FAAH (1.00) | MEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770610-A | ADMINISTERING R-(+)-N-(2-METHYL-2-(5-METHOXY-6-CHLOROINDOL-3-YL)ETHYL) ACETAMIDE | ELI LILLY AND COMPANY (US) | 1998-06-23 | — | — | US | disclosed |