Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806878 | 0.85 | ALDH1A1 (0.48) | RAB9AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6806950 | 0.83 | ATP4A (0.50) | RAB9AALDH1A1TP53GAAMEN1 | |
| SCHEMBL18674619 | 0.79 | RAB9A (0.60) | RAB9AALDH1A1TP53GAAMEN1 | |
| SCHEMBL8716770 | 0.79 | ALDH1A1 (0.43) | RAB9AALDH1A1TP53GAAMEN1 | |
| SCHEMBL8716296 | 0.79 | DHODH (0.46) | ALDH1A1DHODHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18674611 | 0.78 | RAB9A (0.57) | RAB9AALDH1A1TP53GAADHODH | |
| SCHEMBL8719505 | 0.77 | ALDH1A1 (0.50) | RAB9AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8717052 | 0.77 | PPARG (0.54) | RAB9AALDH1A1TP53MEN1KMT2A | |
| SCHEMBL18674610 | 0.76 | RAB9A (0.55) | RAB9AALDH1A1TP53GAADHODH | |
| SCHEMBL18674688 | 0.75 | RAB9A (0.51) | RAB9AALDH1A1TP53GAADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756525-A | USING A THIAZOLIDINEDIONE COMPOUND | BEECHAM GROUP PLC (GB) | 1998-05-26 | — | — | US | disclosed |